Noun
Janus kinase (plural Janus kinases)
(biochemistry) Any of a family of intracellular non-receptor tyrosine kinases that transduce cytokine-mediated signals via the JAK-STAT pathway.
Synonym: (abbreviation) JAK
Hyponyms: JAK1, JAK2, JAK3, TYK2
However each IFN type can also activate unique STATs. citation STAT activation initiates the most well-defined cell signaling pathway for all IFNs, the classical Janus kinase -STAT ( JAK-STAT ) signaling pathway. Source: Internet
Repigmentation in vitiligo using the Janus kinase inhibitor tofacitinib may require concomitant light exposure. Source: Internet
They were initially named "just another kinase" 1 and 2 (since they were just two of a large number of discoveries in a PCR -based screen of kinases, citation ) but were ultimately published as "Janus kinase". Source: Internet