levodopa
Noun
Meaning
the levorotatory form of dopa (trade names Bendopa and Brocadopa and Larodopa); as a drug it is used to treat Parkinson's disease
Source: WordNetSynonyms
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Examples
It was named dopamine because it is a monoamine whose precursor in the Barger-Ewens synthesis is 3,4-dihydroxyphenylalanine (levodopa or L-DOPA ).
Because carbidopa permits more levodopa to reach the brain and more to be formed, certain adverse central nervous system (CNS) effects, e.g., dyskinesias ( movements), may occur at lower dosages and sooner with SINEMET than with levodopa alone.
Being able to accurately assess tremors is crucial when it comes to determining the accurate dosage of Levodopa, an initial pharmacological therapy for patients with Parkinson’s.
Levodopa, theoretically, is transformed into the active form, dopamine, within the basal ganglia, that area of the brain that encloses the substantia nigra.
The drawback of levodopa treatment is that it treats the symptoms of Parkinson's (low dopamine levels), rather than the cause (the death of dopaminergic neurons in the substantia nigra).
The patients, who were rigid and almost completely immobile, responded to levodopa treatment.