Noun
losartan (uncountable)
(pharmacology) An antihypertensive drug that is taken orally in the form of its potassium salt C22H22ClKN6O and blocks the action of the physiologically active form of angiotensin.
It is converted, in part, to an active carboxylic acid metabolite that is responsible for most of the angiotensin II receptor antagonism that follows losartan treatment. Source: Internet
When patients were randomized to continue losartan at the two higher doses or to placebo after 3 weeks of therapy, trough diastolic blood pressure rose in patients on placebo between 5 and 7 mmHg more than patients randomized to continuing losartan. Source: Internet
The pharmacodynamic consequences of concomitant use of losartan and inhibitors of P450 2C9 have not been examined. Source: Internet