lose big
Synonyms
Examples
If you're not adapting to the very rapidly changing environment, if you can't think creatively, you lose big in this society because there are very few jobs for you left.
I started to do a study on how not to do stand-up comedy. Yeah, it's lonely work. You die, you die alone. It's you, the light, and the audience. If you win, you win big. If you lose, you lose big time.