MAO-A
Synonyms
Examples
Some MAOIs inhibit both MAO-A and MAO-B equally, other MAOIs have been developed to target one over the other.
Of note, no dietary modifications are needed when taking a reversible inhibitor of MAO-A (i.
Of the 13 maltreated males with low MAO-A activity, 11 had been assessed as exhibiting adolescent conduct disorder and 4 were convicted for violent offenses.
Seligiline : Originally used a treatment for Parkinson's disease due to its selective, irreversible inhibition of MAO-B but at higher doses MAO-A inhibition occurs.
There are two isoforms of monoamine oxidase, MAO-A and MAO-B.
These compounds do reach the brain, although some portion of them are metabolized by monoamine oxidase enzymes (mainly MAO-A ) in the liver.