mesolimbic
Adjective
Meaning
mesolimbic (not comparable)
(neuroanatomy) Relating to the middle part of the limbic system.
Phrases with the word
Anagrams
Examples
Eric Berne, A Layman's Guide to Psychiatry and Psychoanalyis (1976) p. 69 and 101 Factors that affect libido Endogenous compounds Libido is governed primarily by activity in the mesolimbic dopamine pathway ( ventral tegmental area and nucleus accumbens ).
Dopaminergic projections from the ventral tegmental area (bottom part of the "midbrain" or mesencephalon) to the prefrontal cortex (mesocortical pathway) and to the nucleus accumbens (mesolimbic pathway - "meso" referring to "from the mesencephalon"..
This cotransmission effect was found in the mesolimbic pathway, an area of the brain implicated in reward, where amphetamine is known to affect dopamine neurotransmission.
One action causes the dopamine molecules to be released from inside the vesicles into the cytoplasm of the nerve terminal, which are then transported outside by the mesolimbic dopamine pathway to the nucleus accumbens.
Excess release of dopamine in the mesolimbic pathway has been linked to psychotic experiences.