Noun
antibacterial agent used especially to treat genitourinary infections
Source: WordNetHistory The first quinolone was nalidixic acid - introduced in 1962 for treatment of urinary tract infections in humans. citation Nalidixic acid was discovered by George Lesher and coworkers in a distillate during an attempt at chloroquine synthesis. Source: Internet
Nalidixic acid was added to the OEHHA Prop 65 list as a carcinogen on 15 May 1998. Source: Internet
Nalidixic acid Ciprofloxacin Levofloxacin Trovafloxacin The quinolones are a family of synthetic broad-spectrum antibiotic drugs. Source: Internet
Nalidixic acid is thus considered to be the predecessor of all members of the quinolone family, including the second, third and fourth generations commonly known as fluoroquinolones. Source: Internet
They proved to be only marginal improvements over nalidixic acid. citation Since the introduction of nalidixic acid in 1962, more than 10,000 analogs have been synthesized, but only a handful have found their way into clinical practice. Source: Internet