Adjective
nigrostriatal (not comparable)
Pertaining to a neural connection between the substantia nigra and the striatum.
Altogether, these results argue for an alteration of the nigrostriatal dopaminergic pathway in MeCP2-deficient animals as a contributor of the neuromotor deficits. Source: Internet
Another well-known afferent is the nigrostriatal connection arising from the neurons of the substantia nigra pars compacta. Source: Internet
All of the effective antipsychotics, except clozapine, act on the nigrostriatal system. Source: Internet
In primates, dopaminergic neuron activity increases in the nigrostriatal pathway when a new stimulus is presented. citation Dopaminergic activity decreases with repeated stimulus presentation. Source: Internet
Today, MPTP remains the most favored neurotoxin to model nigrostriatal degeneration and dopamine depletion in animals, for studying Parkinson's disease. Source: Internet