nondisjunction
Noun
Meaning
meiosis in which there is a failure of paired homologous chromosomes to separate; results in an abnormal number of chromosomes in the daughter cells
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Examples
Autosomal genetic disorders can arise due to a number of causes, some of the most common being nondisjunction in parental germ cells or Mendelian inheritance of deleterious alleles from parents.
An incident in chromosome separation during anaphase II (of meiosis II ) called nondisjunction can result in sperm cells with an extra copy of the Y-chromosome.
When the segregation is not normal, it is called nondisjunction.