A 2011 publication citation in the Journal of Urology received widespread publicity. citation According to this study, men who used NSAIDs regularly were at significantly increased risk of erectile dysfunction. Source: Internet
Afflicted individuals may be abnormally sensitive to these provocative metabolites and/or overproduce them and typically are susceptible to a wide range of structurally dissimilar NSAIDs, particularly those that inhibit COX1. Source: Internet
Anti-inflammatory agents NSAIDs reduce both pain and stiffness in those with RA. Source: Internet
Also, high homocysteine can be caused by a number of drugs and supplements, including niacin, metformin, insulin, corticosteroids, NSAIDs, and some anticonvulsants cause high homocysteine levels too. Source: Internet
After birth of son six years ago acceleration of aches and pains began; allergic to (sulfas) and now GI intolerant to NSAIDS, so therapy has accelerated as well. Source: Internet
Combining aspirin with other NSAIDs has also been shown to further increase this risk. Source: Internet