nuclease
Noun
Meaning
general term for enzymes that catalyze the hydrolysis of nucleic acid by cleaving chains of nucleotides into smaller units
Source: WordNetHypernyms
Hyponyms
Phrases with the word
Examples
Cleavage of the RNA flaps involves either endonuclease 1 (FEN1) cleavage of short flaps, or coating of long flaps by the single-stranded DNA binding protein replication protein A (RPA) and sequential cleavage by Dna2 nuclease and FEN1.
Gam is also important in that it inhibits the host RecBCD nuclease from degrading the 3’ ends in rolling circle replication.
Topoisomerases and helicases Topoisomerases are enzymes with both nuclease and ligase activity.
RNA sequencing RNA is less stable in the cell, and also more prone to nuclease attack experimentally.
The 5′ end of the nicked strand is transferred to a tyrosine residue on the nuclease and the free 3′ OH group is then used by the DNA polymerase to synthesize the new strand.