nuclease

Noun

Meaning

general term for enzymes that catalyze the hydrolysis of nucleic acid by cleaving chains of nucleotides into smaller units

Source: WordNet

Hypernyms

Hyponyms

Phrases with the word

Examples

Cleavage of the RNA flaps involves either endonuclease 1 (FEN1) cleavage of short flaps, or coating of long flaps by the single-stranded DNA binding protein replication protein A (RPA) and sequential cleavage by Dna2 nuclease and FEN1. Source: Internet

Gam is also important in that it inhibits the host RecBCD nuclease from degrading the 3’ ends in rolling circle replication. Source: Internet

Topoisomerases and helicases Topoisomerases are enzymes with both nuclease and ligase activity. Source: Internet

RNA sequencing RNA is less stable in the cell, and also more prone to nuclease attack experimentally. Source: Internet

The 5′ end of the nicked strand is transferred to a tyrosine residue on the nuclease and the free 3′ OH group is then used by the DNA polymerase to synthesize the new strand. Source: Internet

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