obstacle
Noun
Meaning
That which stands in the way, or opposes; anything that hinders progress; a hindrance; an obstruction, physical or moral.
Source: Webster's dictionarySynonyms
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The biggest obstacle in life is fear. The ugliest feeling is hate. The biggest mistake is to give up. The most beautiful gift is forgiveness. The greatest strength is faith. The most beautiful thing in the world is love.
The greatest obstacle to discovery is not ignorance - it is the illusion of knowledge.
Fear is no obstacle to death.
A partner in the business will not put an obstacle to it.
Merit is often an obstacle to fortune; the reason is it produces two bad effects, envy and fear.