Noun
The quality of having a dominant hand; left-handedness or right-handedness.
Chirality
The possession of only one hand or the ability to use only one hand; the loss of the use of one hand.
The state of choosing to use only one hand.
The quality of being designed for only one hand.
A state in which only one person is active
(metaphoric) Weakness, limitation
Source: en.wiktionary.org