In Parkinson's disease the activity in direct pathways to interior globus pallidus decreases and activity in indirect pathways to external globus pallidus increases. Source: Internet
It was found that "increasing movement extent was associated with parallel increases of rCBF in bilateral basal ganglia (BG; putamen and globus pallidus) and ipsilateral cerebellum." Source: Internet
Anatomy Globus pallidus (lower left) and putamen (upper right). Source: Internet
The direct pathway consists of two inhibitory pathways from the putamen to the substantia nigra and the internal region of the globus pallidus. Source: Internet
The pars compacta sends excitatory input to the striatum via D1 pathway that excites and activates the striatum, resulting in the release of GABA onto the globus pallidus to inhibit its inhibitory effects on the thalamic nucleus. Source: Internet
The striatum includes the caudate nucleus (top) and putamen (right) and the globus pallidus (left). Source: Internet