paratope
Noun
Meaning
paratope (plural paratopes)
(biochemistry) That part of the molecule of an antibody that binds to an antigen
Synonyms
Related terms
Examples
4. Light chain (green) with one variable (V L ) and one constant (C L ) domain 5. Antigen binding site (paratope) 6. Hinge regions.
Antibody–antigen interactions The antibody's paratope interacts with the antigen's epitope.
It is composed of one constant and one variable domain from each heavy and light chain of the antibody. citation The paratope is shaped at the amino terminal end of the antibody monomer by the variable domains from the heavy and light chains.
These gene segments are then joined together using random genetic recombination to produce the paratope.