Noun
the primary linkage of all protein structures; the chemical bond between the carboxyl groups and amino groups that unites a peptide
Source: WordNetAlthough catalysis of the peptide bond involves the C2 hydroxyl of RNA's P-site adenosine in a proton shuttle mechanism, other steps in protein synthesis (such as translocation) are caused by changes in protein conformations. Source: Internet
Due to the ring formation connected to the beta carbon, the ψ and φ angles about the peptide bond have fewer allowable degrees of rotation. Source: Internet
By contrast, the cis and trans isomers of the X-Pro peptide bond (where X represents any amino acid) both experience steric clashes with the neighboring substitution and are nearly equal energetically. Source: Internet
However, additional molecular interactions may render the amide form less stable; the amino group is expelled instead, resulting in an ester (Ser/Thr) or thioester (Cys) bond in place of the peptide bond. Source: Internet
Catalysis Catalysis is achieved by one of two mechanisms: *Aspartic, glutamic and metallo- proteases activate a water molecule which performs a nucleophilic attack on the peptide bond to hydrolyse it. Source: Internet
It also affects the rate of peptide bond formation between proline and other amino acids. Source: Internet