Adjective
(of a place or community) Experiencing an epidemic or epidemics of bubonic plague or another illness.
(of a time) During which there is an epidemic or epidemics of bubonic plague or another illness.
(of a person, animal, body or object) Infected with or suffering from bubonic plague or another epidemic illness.
Source: en.wiktionary.orgI don't want a fortnight on the Costa del Sol Don't wanna go to Bognor - it's a plague-ridden hole and it don't fit in with my ideology... Down the Adriatic to the Vlora bay Twenty pints of Fosters and I'm away 'Cos now I know just where I wanna be: Albania - that's the place for me! Attila the Stockbroker
It was also plague-ridden, expensive to fortify and the garrison in San Juan kept deserting because the Spanish kings rarely paid their troops. Source: Internet
Here's the first part of the publisher's description (emphasis mine): "Set on a remote island in a post-apocalyptic, plague-ridden world, this electrifying novel is destined to become a modern classic." Source: Internet