polyacrylamide
Noun
Meaning
English Wikipedia has an article on:polyacrylamideWikipedia
polyacrylamide (plural polyacrylamides)
(organic chemistry) Any of a range of cross-linked polymers of acrylamide; used to form soft gels for making contact lenses etc.
Synonyms
Examples
Acrylamide, in contrast to polyacrylamide, is a neurotoxin and must be handled using appropriate safety precautions to avoid poisoning.
Agarose gel has lower resolving power than polyacrylamide gel for DNA but has a greater range of separation, and is therefore used for DNA fragments of usually 50-20,000 bp in size.
For example, ICP-MS may be combined with size exclusion chromatography and quantitative preparative native continuous polyacrylamide gel electrophoresis ( QPNC-PAGE ) for identifying and quantifying native metal cofactor containing proteins in biofluids.
See the " Chain termination method " page for an example of a polyacrylamide DNA sequencing gel.
Traditional DNA sequencing techniques such as Maxam-Gilbert or Sanger methods used polyacrylamide gels to separate DNA fragments differing by a single base-pair in length so the sequence could be read.
Another use of polyacrylamide is as a chemical intermediate in the production of N-methylol acrylamide and N-butoxyacrylamide.