preclinical
Adjective
Meaning
of or relating to the early phases of a disease when accurate diagnosis is not possible because symptoms of the disease have not yet appeared
Source: WordNetSynonyms
Examples
A preclinical study published this week reported promising findings with a sucralfate pill paired with a novel luminal intestine coating compound that prevented absorption of nutrients in the intestines, preventing post-meal blood glucose spikes in rats.
Non-invasive cancer treatment This preclinical treatment involves using radio waves to heat up tiny metals that are implanted in cancerous tissue.
In preclinical models, KO-539 inhibits the KMT2A/MLL protein complex and has downstream effects on HOXA9/MEIS1 expression.
A few that we are especially excited about – silmitasertib, gilteritinib, ralimetinib, apilimod and dinaciclib – are either approved for treatment, in clinical testing or under preclinical development for various diseases.
And in addition to these lines of inquiry, there are already eight potential vaccines under clinical evaluation and more than 100 vaccine candidates in preclinical stages.
As I noted, preclinical studies are underway and we now expect to file an IND in 2021.