proapoptotic
Adjective
Meaning
proapoptotic (comparative more proapoptotic, superlative most proapoptotic)
That leads to apoptosis
Examples
As a consequence, p53 cannot induce apoptosis, since it cannot induce the expression of proapoptotic proteins.
As a consequence, the balance of anti-apoptotic and proapoptotic effectors is upset in favour of the former, and the damaged cells continue to replicate despite being directed to die.
These homologs can inhibit proapoptotic proteins such as BAX and BAK, which are essential for the activation of apoptosis.
The proapoptotic homodimers are required to make the mitochondrial membrane permeable for the release of caspase activators such as cytochrome c and SMAC.