1. prodrug - Noun
2. prodrug - Adjective
prodrug (plural prodrugs)
(pharmacology) A drug that is administered in an inactive form that is metabolised in the body into a biologically active compound
prodrug (comparative more prodrug, superlative most prodrug)
In favour of recreational drugs.
Another strategy is to use anaerobic bacteria that have been transformed with an enzyme that can convert a non-toxic prodrug into a toxic drug. Source: Internet
Antimony and its compounds do not cause acute human health effects, with the exception of antimony potassium tartrate ("tartar emetic"), a prodrug that is intentionally used to treat leishmaniasis patients. Source: Internet
In addition to serving as an important active metabolite of aspirin (acetylsalicylic acid), which acts in part as a prodrug to salicylic acid, it is probably best known for its use as a key ingredient in topical anti-acne products. Source: Internet
This creates a problem: Chloramphenicol succinate ester is an inactive prodrug and must first be hydrolysed to chloramphenicol; however, the hydrolysis process is often incomplete, and 30% of the dose is lost and removed in the urine. Source: Internet
Amphetamine is also prescribed in enantiopure and prodrug form as dextroamphetamine and lisdexamfetamine respectively. Source: Internet
Thus, a systemically applied prodrug is metabolised to the toxic drug only in the tumour. Source: Internet