proteolysis
Noun
Meaning
The digestion or dissolving of proteid matter by proteolytic ferments.
Source: Webster's dictionarySynonyms
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Examples
A chemically synthesized c-terminal tail is then grafted onto insulin by reverse proteolysis using the inexpensive protease trypsin; typically the lysine on the c-terminal tail is protected with a chemical protecting group to prevent proteolysis.
Each catalytic β subunit also possesses a conserved lysine residue required for proteolysis.
Biological functions Post-translational proteolytic processing Limited proteolysis of a polypeptide during or after translation in protein synthesis often occurs for many proteins.
Consequently, dis-regulation of proteolysis can cause diseases and is used in some venoms to damage their prey.
However, high levels of oxidative damage increases the degree of cross-linking between protein fragments, rendering the aggregates resistant to proteolysis.
Low pH or high temperatures can also cause proteolysis non-enzymatically.