public enemy number one
Noun
Meaning
(US, law enforcement, dated) A person who ranks highest on the federal government's prioritized list of wanted criminal fugitives.
(by extension) A person, organization, or other object considered to be particularly menacing, harmful, or loathsome.
Source: en.wiktionary.orgExamples
It is Public Enemy Number One to the survival of our planetary civilization.
"Looking back on history, who was treated worse, Alfonse Capone, legendary mob boss, killer and 'Public Enemy Number One,' or Paul Manafort, political operative & Reagan/Dole darling, now serving solitary confinement - although convicted of nothing?"