quetiapine
Noun
Meaning
quetiapine (uncountable)
(pharmacology) An antipsychotic drug taken orally in the form of its fumarate (C21H25N3O2S)2·C4H4O4 especially to treat schizophrenia and bipolar disorder. It is marketed under the trademark Seroquel.
Synonyms
Examples
Somnolence was a commonly reported adverse reaction reported in patients treated with quetiapine especially during the 3-day period of initial dose titration.
These hepatic enzyme elevations usually occurred within the first 3 weeks of drug treatment and promptly returned to pre-study levels with ongoing treatment with quetiapine.
The acute treatment of a manic episode of bipolar disorder involves the utilization of either a mood stabilizer (valproate, lithium, or carbamazepine) or an atypical antipsychotic (olanzapine, quetiapine, risperidone, or aripiprazole).
The atypical antipsychotic quetiapine appears effective in generalized anxiety disorder; however, rates of adverse effects are greater than that with SSRIs. citation Evidence for risperidone and olanzapine is not enough to make any comments.
There is no race effect on the pharmacokinetics of quetiapine.
When adjusted for weight, the AUC and Cmax of quetiapine were 41% and 39% lower, respectively, in children and adolescents compared to adults.