raloxifene
Noun
Meaning
raloxifene (uncountable)
(pharmacology) A drug used orally in the form of its hydrochloride C28H27NO4S·HCl as prophylaxis against osteoporosis after menopause.
Synonyms
Examples
The pharmacokinetics of raloxifene has not been studied in patients with moderate or severe hepatic impairment.
Raloxifene prevents vertebral fractures in postmenopausal, osteoporotic women and reduces the risk of invasive breast cancer. citation Other medication Some of the SSRIs and SNRIs appear to provide some relief.
Raloxifene exhibits oestrogen agonist activity on bone and lipids, and antagonist activity on breast and the endometrium. citation Tamoxifen is in widespread use for treatment of hormone sensitive breast cancer.
The skeletal effects of raloxifene treatment were assessed in ovariectomized rats and monkeys.