retrovirus
Noun
Meaning
any of a group of viruses that contain two single-strand linear RNA molecules per virion and reverse transcriptase (RNA to DNA); the virus transcribes its RNA into a cDNA provirus that is then incorporated into the host cell
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Examples
One could not have isolated this retrovirus without knowledge of other retroviruses, that's obvious. But I believe we have answered the criteria of isolation.
Because reverse transcription lacks the usual proofreading of DNA replication, a retrovirus mutates very often.
In 1965, Howard Temin described the first retrovirus : a virus whose RNA genome was reverse transcribed into complementary DNA (cDNA), then integrated into the host's genome and expressed from that template.
These activities are used by the retrovirus to convert single-stranded genomic RNA into double-stranded cDNA which can integrate into the host genome, potentially generating a long-term infection that can be very difficult to eradicate.
Martin and Handasyde p. 114. The koala retrovirus (KoRV) may cause koala immune deficiency syndrome (KIDS) which is similar to AIDS in humans.
Multiplication A retrovirus has a membrane containing glycoproteins, which are able to bind to a receptor protein on a host cell.