1. roofie - Noun
2. roofie - Verb
(slang, often in the plural) Rohypnol.
Synonyms: rope, roaches, Rufalin
(slang, by extension) Any drug designed to make someone drowsy or disoriented; a date rape drug.
(slang, transitive) To put roofies in; to spike with roofies.
Someone roofied her drink, but she found out and poured it away.
(slang, transitive) To cause someone to (usually unknowingly) ingest roofies.
Source: en.wiktionary.org