salmeterol
Noun
Meaning
salmeterol (uncountable)
(pharmacology) A bronchodilator administered by oral inhalation in the form of a salt C25H37NO4·C11H8O3 to treat bronchospasm associated especially with asthma and chronic obstructive pulmonary disease. It acts as an agonist, binding to beta-receptors that mediate the relaxation of bronchial muscles.
Examples
ADVAIR HFA contains both fluticasone propionate and salmeterol.
Subjects treated with high doses of ICS with or without concurrent salmeterol received ADVAIR HFA 230/21.
Improvements in lung function (as defined by predose and postdose FEV) were significantly greater with ADVAIR DISKUS than with fluticasone propionate, salmeterol, or placebo.
The third trial was a 1-year trial that evaluated ADVAIR DISKUS 500/50, fluticasone propionate 500 mcg, salmeterol 50 mcg, and placebo in 1,465 subjects.
Peak plasma salmeterol concentrations were increased by 1.4-fold (90% CI: 1.23, 1.68).