Verb
To fiddle with; to tinker; to affect negatively.
Quit screwing with the volume.
To mess with; to have on; to trick; to play with a lighthearted or joking manner.
This bigfoot talk is just him screwing with us again.
Sometimes I talk to myself fluently in languages I'm unfamiliar with... just to screw with my subconscious. Steven Wright
This stammer got me a home in Beverly Hills, and I'm not about to screw with it now. Bob Newhart
I don't have a computer - I don't like to get into it that much 'cause it can screw with your head a little. James Marsters
Now, therefore, the Directors of the company are hereby ordered to see that precautions are taken to make travel on said railroad perfectly safe by using a screw with at least twenty-four inches diameter. Emperor Norton