serotonergic
Speech parts
1. serotonergic - Noun
2. serotonergic - Adjective
Meaning
Containing or releasing serotonin.
Involved in, or capable of modulating activity in, neurotransmission pathways that use serotonin receptor proteins.
serotonergic (plural serotonergics)
That which is serotonergic.
Synonyms
Phrases with the word
Examples
All currently marketed antidepressants have the monoamine hypothesis as their theoretical basis, with the possible exception of agomelatine which acts on a dual melatonergic serotonergic pathway.
As the serotonergic system may be involved in the regulation of sleep, mood, and anxiety, the stimulation of this system by high doses of GHB may be involved in certain neuropharmacological events induced by GHB administration.
Treatment with PROZAC and any concomitant serotonergic agents, should be discontinued immediately if the above events occur and supportive symptomatic treatment should be initiated.
For example, the transcription factor FEV (aka Pet1) has been shown, through its role in maintaining the serotonergic system in the brain, to be required for normal aggressive and anxiety-like behavior.
However, the PMAT, despite its relatively low serotonergic affinity, has a considerably higher transport 'capacity' than SERT, ", resulting in roughly comparable uptake efficiencies to SERT in heterologous expression systems."
Serotonin syndrome is typically caused by the use of two or more serotonergic medications or drugs.