One of the most dynamic and significant changes you can make in your life is to make the commitment to drop all negative references to your past, to begin living now. Richard Carlson
The threat of hunger cannot be eliminated without the assistance of the developed countries, and this requires significant changes in their foreign and domestic policies. Andrei Sakharov
I think it is fair to say that it is under a great deal of stress, and if I am asking for significant changes, it is because the world is going through significant changes. Mohamed ElBaradei
In the same period, Polish literature also underwent some significant changes. From social-political literature, which had a great tradition and strong motivation to be that way, Polish literature changed its focus to a psychological rather than a social one. Andrzej Wajda
Business has to change the way it does business, or we will make no significant changes in the way we relate to the earth. Dennis Weaver
There are some very significant changes in the way the fluids are distributed in our body, the way our heart functions initially, and as well as our bone and muscle. Laurel Clark