simvastatin
Noun
Meaning
an oral lipid-lowering medicine (trade name Zocor) administered to reduce blood cholesterol levels; recommended after heart attacks
Source: WordNetSynonyms
Hypernyms
Examples
Animal reproduction studies of simvastatin in rats and rabbits showed no evidence of teratogenicity.
Coadministration of multiple doses of 10 mg of amlodipine with 80 mg simvastatin resulted in a 77% increase in exposure to simvastatin compared to simvastatin alone.
In addition, simvastatin significantly decreased the proportion of patients with new lesions and with new total occlusions.
Postmarketing surveillance of lovastatin and simvastatin exposure during pregnancy.
The Heart Protection Study () was a large, multi-center, placebo-controlled, double-blind study with a mean duration of 5 years conducted in 20,536 patients (10,269 on simvastatin 40 mg and 10,267 on placebo).
There were no significant differences between the treatment groups for all-cause mortality: 366 (8.2%) in the LIPITOR 80mg/day group vs. 374(8.4%)in the simvastatin 20-40 mg/day group.