Noun
an oral lipid-lowering medicine (trade name Zocor) administered to reduce blood cholesterol levels; recommended after heart attacks
Source: WordNetAnimal reproduction studies of simvastatin in rats and rabbits showed no evidence of teratogenicity. Source: Internet
Coadministration of multiple doses of 10 mg of amlodipine with 80 mg simvastatin resulted in a 77% increase in exposure to simvastatin compared to simvastatin alone. Source: Internet
In addition, simvastatin significantly decreased the proportion of patients with new lesions and with new total occlusions. Source: Internet
Postmarketing surveillance of lovastatin and simvastatin exposure during pregnancy. Source: Internet
The Heart Protection Study () was a large, multi-center, placebo-controlled, double-blind study with a mean duration of 5 years conducted in 20,536 patients (10,269 on simvastatin 40 mg and 10,267 on placebo). Source: Internet
There were no significant differences between the treatment groups for all-cause mortality: 366 (8.2%) in the LIPITOR 80mg/day group vs. 374(8.4%)in the simvastatin 20-40 mg/day group. Source: Internet