Striking out often means failing at repeated attempts, like in dating or sales. In baseball, it is being put out after three strikes. It can also mean setting off on your own toward a new path.
Life is for the living. Don't let the fear of striking out let you from keep you from playing the game. Laurie Halse Anderson
Don't let the fear of striking out hold you back. Babe Ruth
What I discovered I liked best about striking out on my bicycle was that the farther I got from home, the more interesting and unusual my thoughts became. Richard Russo
As soon as I got out there I felt a strange relationship with the pitcher's mound. It was as if I'd been born out there. Pitching just felt like the most natural thing in the world. Striking out batters was easy. Babe Ruth
I hate striking out, doesn't matter what time of the game. I just don't like striking out. Joe Mauer
Stopping at third base adds no more to the score than striking out. American Proverb