Noun
A salt of succinic acid.
Source: Webster's dictionaryAfter oral administration of C-solifenacin succinate to pregnant mice, drug-related material was shown to cross the barrier. Source: Internet
Intravenous The intravenous (IV) preparation of chloramphenicol is the succinate ester, because pure chloramphenicol does not dissolve in water. Source: Internet
The NAD pathway in the genus nicotiana begins with the oxidation of aspartic acid into α-imino succinate by aspartate oxidase (AO). Source: Internet
This creates a problem: Chloramphenicol succinate ester is an inactive prodrug and must first be hydrolysed to chloramphenicol; however, the hydrolysis process is often incomplete, and 30% of the dose is lost and removed in the urine. Source: Internet
Succinate can therefore be oxidized to fumarate if a strong oxidizing agent such as oxygen is available, or fumarate can be reduced to succinate using a strong reducing agent such as formate. Source: Internet
In addition, the efficacy of doxycycline and erythromycin succinate may be reduced by alcohol consumption. citation Other effects of alcohol on antibiotic activity include altered activity of the liver enzymes that break down the antibiotic compound. Source: Internet