tetrahydrobiopterin
Noun
Meaning
tetrahydrobiopterin (uncountable)
English Wikipedia has an article on:tetrahydrobiopterinWikipedia
(biochemistry) A naturally-occurring nutrient and essential cofactor of the three aromatic amino acid hydroxylase enzymes, used in the biosynthesis of the neurotransmitters serotonin, melatonin, dopamine, norepinephrine, epinephrine, and nitric oxide.
Synonyms
Examples
Tetrahydrobiopterin is a cofactor in the production of L-DOPA from tyrosine and 5-hydroxy-L-tryptophan from tryptophan, which must be supplemented as treatment in addition to the supplements for classical PKU.
Tetrahydrobiopterin deficiency can be caused by defects in four genes.