thymic
Adjective
Meaning
Of or pertaining to the thymus gland.
Pertaining to, or derived from, thyme; as, thymic acid.
Source: Webster's dictionarySynonyms
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Examples
Development The two main components of the thymus, the lymphoid thymocytes and the thymic epithelial cells, have distinct developmental origins.
For example, mouse thymic epithelial cells (TECs) are known to react with antibodies for keratin 5, keratin 8, and keratin 14. These antibodies are used as fluorescent markers to distinguish subsets of TECs in genetic studies of the thymus.
By the early teens, the thymus begins to atrophy and thymic stroma is mostly replaced by adipose (fat) tissue.
Immunodeficiency As the thymus is the organ of T-cell development, any congenital defect in thymic genesis or a defect in thymocyte development can lead to a profound T cell deficiency in primary immunodeficiency disease.
In addition, thymic stromal cells allow for the selection of a functional and self-tolerant T cell repertoire.
In mice, the nude mouse strain are congenitally thymic deficient.