To ruin
Examples
It takes 20 years to build a reputation and five minutes to ruin it. If you think about that, you'll do things differently.
Reality continues to ruin my life.
There are numerous bugbears in the profession of a politician. First, ordinary life suffers. Second, there are many temptations to ruin you and those around you. And I suppose third, and this is rarely discussed, people at the top generally have no friends.
The road to ruin is paved with good intentions.
To spend much and gain little is the sure road to ruin.
The road to ruin is kept in good repair, and the travellers pay the expense.