Noun
The activation of something by another entity that has a spatial relationship with it
(genetics) The activation of a gene by the presence of another at a different locus, especially following infection by a virus
Source: en.wiktionary.orgA coactivator protein interacting with the activation function 1 (AF-1) transactivation domain of the androgen receptor may have been deficient in this patient. Source: Internet
Conversely, the steroid-binding domain may act to repress the AR transactivation domain, perhaps due to the AR's unliganded conformation. Source: Internet
Starting from the N-terminus, there are first the amino-terminal transactivation domains (TAD 1, TAD 2), which are needed to induce a subset of p53 target genes. Source: Internet
The transactivation domain is encoded by exon 1, and makes up more than half of the AR protein. Source: Internet
In addition, the transactivation and signal-sensing functions are frequently contained within the same domain. Source: Internet
The ligand-binding domain is additionally responsible for dimerization of nucleic receptors prior to binding and providing structures for transactivation used for communication with the translational apparatus. Source: Internet