transcriptional
Adjective
Meaning
transcriptional (not comparable)
Of or pertaining to transcription, especially to the transcription of genetic information
Examples
Addiction Addiction is a disorder of the brain's reward system which arises through transcriptional and neuroepigenetic mechanisms and occurs over time from chronically high levels of exposure to an addictive stimulus (e.
A subfamily of HADs, the Eyes Absent Family (Eya), are also transcription factors and can therefore regulate their own phosphorylation and that of transcriptional cofactor/s, and contribute to the control of gene transcription.
A conserved transcriptional response to intranasal Ebola virus exposure in nonhuman primates prior to onset of feverScience Translational Medicine, 2018; 10 (434): eaaq1016 DOI: 10.1126/scitranslmed.
Calreticulin can inhibit the binding of androgen receptor to its hormone-responsive DNA element and can inhibit androgen receptor and retinoic acid receptor transcriptional activities in vivo, as well as retinoic acid-induced neuronal differentiation.
For example, acetylation of the K14 and K9 lysines of the tail of histone H3 by histone acetyltransferase enzymes (HATs) is generally related to transcriptional competence.
However, it is an excellent mark of active promoters and the level of this histone modification at a gene’s promoter is broadly correlated with transcriptional activity of the gene.