Noun
transmethylation (plural transmethylations)
(organic chemistry, biochemistry) The transfer of a methyl group between molecules, especially between biological compounds such as amino acids or the components of nucleic acids.
Also, robust evidence that INMT can catalyze transmethylation of tryptamine into NMT and DMT could be provided with reverse isotope dilution analysis coupled to mass spectrometry for rabbit citation citation and human citation lung during the early 1970s. Source: Internet
Tryptamine then undergoes a transmethylation (step 2): the enzyme indolethylamine-N-methyltransferase (INMT) catalyzes the transfer of a methyl group from cofactor S-adenosyl-methionine (SAM), via nucleophilic attack, to tryptamine. Source: Internet
Tryptamine transmethylation is regulated by two products of the reaction: SAH, citation citation citation and DMT were shown ex vivo to be among the most potent inhibitors of rabbit INMT activity. Source: Internet
This transmethylation mechanism has been repeatedly and consistently proven by radiolabeling of SAM methyl group with carbon-14 ( 14 C-CH 3 )SAM). Source: Internet