transposase
Noun
Meaning
transposase (countable and uncountable, plural transposases)
(biochemistry) An enzyme required for the transposition of transposons
Examples
In vertebrate animal cells, nearly all 100,000+ DNA transposons per genome have genes that encode inactive transposase polypeptides. citation In humans, all Tc1-like transposons are inactive.
The insertion sites of DNA transposons may be identified by short direct repeats (created by the staggered cut in the target DNA and filling in by DNA polymerase) followed by a series of inverted repeats important for the TE excision by transposase.
The transposase makes a staggered cut at the target site resulting in single-strand 5' or 3' DNA overhangs, so-called " sticky ends ".
Ds has a mutation in its transposase gene, which means that it cannot move without another source of transposase.