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transposon

Noun

Meaning

a segment of DNA that can become integrated at many different sites along a chromosome (especially a segment of bacterial DNA that can be translocated as a whole)

Source: WordNet

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In some cases, a replicative transposition is observed in which a transposon replicates itself to a new target site (e.g. helitron (biology) ). Source: Internet

It is not yet understood why these elements are spliced, whether by chance, or by some preferential action by the transposon. Source: Internet

Sometimes the insertion of a TE into a gene can disrupt that gene's function in a reversible manner, in a process called insertional mutagenesis ; transposase-mediated excision of the DNA transposon restores gene function. Source: Internet

This step cuts out the DNA transposon, which is then ligated into a new target site; the process involves activity of a DNA polymerase that fills in gaps and of a DNA ligase that closes the sugar-phosphate backbone. Source: Internet

Such an insertion could intronize the transposon without disrupting the coding sequence when a transposon inserts into the sequence AGGT, resulting in the duplication of this sequence on each side of the transposon. Source: Internet

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