Noun
trinucleotide (plural trinucleotides)
(genetics) a codon containing three nucleotides
Among the microsatellite sequences, trinucleotide repeats are of particular importance, as sometimes occur within coding regions of genes for proteins and may lead to genetic disorders. Source: Internet
Huntington's disease has autosomal dominant inheritance, meaning that an affected individual typically inherits one copy of the gene with an expanded trinucleotide repeat (the mutant allele ) from an affected parent. Source: Internet
Differential diagnosis About 99% of HD diagnoses based on the typical symptoms and a family history of the disease are confirmed by genetic testing to have the expanded trinucleotide repeat that causes HD. Source: Internet
This usually leads to new expansions as generations pass ( dynamic mutations ) instead of reproducing an exact copy of the trinucleotide repeat. Source: Internet