tubulin
Noun
Meaning
(biochemistry) Any of a group of proteins used as the material for microtubules.
(biochemistry) Specifically, the dimer of α-tubulin and β-tubulin.
Source: en.wiktionary.orgSynonyms
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GTP-bound tubulin can begin adding to the tip of the microtubule again, providing a new cap and protecting the microtubule from shrinking.
During polymerization, the tubulin dimers are in the GTP -bound state.
Each tubulin also has a tail extending out from the microtubules, which is negatively charged, and therefore attracts positively charged ions.
However, in most microtubules there is a seam in which tubulin subunits interact α-β. citation Some species of Prosthecobacter also contain microtubules.
In the gel state, it was further hypothesized that the water electrical dipoles are oriented in the same direction, along the outer edge of the microtubule tubulin subunits.
It has anti-microtubule activity, and its mechanism is similar to that of vinca alkaloids in that they bind to tubulin, inhibiting microtubule formation.