(slang) In favour or good repute; strait-laced.
(slang) In confusion or error.
(slang) In trouble or difficulty.
(slang, archaic) Drunk.
(slang, US, military, dated) Teetotal; not drinking any alcohol.
(slang) Crazy; at one's wits' end.
(slang, Ireland, dated) Pregnant.
Source: en.wiktionary.orgWriters are like eremites or anchorites - natural-born eremites or anchorites - who seem puzzled as to why they went up the pole or into the cave in the first place. Joy Williams