Noun
VLCFA (plural VLCFAs)
(organic chemistry) Initialism of very-long-chain fatty acid.
Coordinate terms: SCFA, MCFA, LCFA
After the realization that endogenous synthesis was an important contribution to VLCFA in the body, efforts at dietary therapy shifted to inhibiting these synthetic pathways in the body. Source: Internet
Although the clinical phenotype is highly variable among affected males, the elevations of VLCFA are present in all males with an ABCD1 mutation. Source: Internet
Successful treatment of the demyelination process that affects the brain with either stem cell transplant or gene therapy does not immediately normalize the VLCFA levels in body tissues. Source: Internet
Dietary intake is not the only source for VLCFA in the body, as they are also synthesized endogenously. Source: Internet
In females, where plasma VLCFA measurement is not always conclusive (some female carriers will have normal VLCFA in plasma), molecular analysis is preferred, particularly in cases where the mutation in the family is known. Source: Internet
This dietary restriction did not impact the levels of VLCFA in plasma and other body tissues. Source: Internet