X-linked
Adjective
Meaning
relating to genes or characteristics or conditions carried on the X chromosome
Source: WordNetSynonyms
Antonyms
Examples
an X-linked mutation
A woman with an X-linked dominant disorder has a 50% chance of having an affected fetus with each pregnancy, although it should be noted that in cases such as incontinentia pigmenti, only female offspring are generally viable.
As an X-linked disorder, ALD presents most commonly in males, however approximately 50% of heterozygote females show some symptoms later in life.
As time went on, new symptoms arose (neutropenia, hypotonia, failure to thrive, small stature and frequent infections), which led the doctors to suspect my boys had some type of X-linked genetic syndrome.
Duchenne muscular dystrophy (DMD) is an autosomal dominant, X-linked neuromuscular disorder caused by mutations in dystrophin, one of the largest genes known to date.
Exceptions to this finding are extremely rare cases in which boys with Klinefelter syndrome (47,XXY) also inherit an X-linked dominant condition and exhibit symptoms more similar to those of a female in terms of disease severity.