affliction Synonyms

misery wretchedness hardship pain sorrow grief misfortune adversity distress calamity trouble suffering symptomatology syndrome sickness sorriness suppuration tensity tribulation trial tragedy torture murrain torment throe unhappiness sickliness seediness scourge penalties pathology pang ordeal neurosis nemesis neediness necessitarianism persecution pestilence plague sadness rockiness rigor retardment purgatory problem pressure predestinarianism mutilation undoing