acetylcholinesterase
Noun
Meaning
acetylcholinesterase (countable and uncountable, plural acetylcholinesterases)
(biochemistry) An enzyme that catalyzes the hydrolysis of the neurotransmitter acetylcholine into choline and acetic acid.
Synonyms
Related terms
Phrases with the word
Examples
After release acetylcholine is broken down by the enzyme acetylcholinesterase Like many other biologically active substances, acetylcholine exerts its effects by binding to and activating receptors located on the surface of cells.
Nonradioactive northern blotting for the determination of acetylcholinesterase mRNA.
They allow endogenously released acetylcholine more time to interact with its respective receptor before being inactivated by acetylcholinesterase in the synaptic cleft (the space between nerve and muscle).
Nerve agents disrupt the nervous system by inhibiting the function of the enzyme acetylcholinesterase by forming a covalent bond where acetylcholine would break down (undergoes hydrolysis ).
Once the impulse is sent, the enzyme acetylcholinesterase immediately breaks down the acetylcholine in order to allow the muscle or organ to relax.
Usually, acetylcholinesterase inhibitors are started at a low dose and increased until the desired result is achieved.