adalimumab
Noun
Meaning
adalimumab (uncountable)
(pharmacology) An immunosuppressive drug (trademark Humira) that is a genetically engineered monoclonal antibody administered by subcutaneous injection to treat the symptoms of various autoimmune diseases (such as rheumatoid arthritis, Crohn's disease, and psoriasis). It acts by binding to and blocking the activity of tumor necrosis factor.
Synonyms
Examples
ADACTA, a phase IV study evaluating the reduction in rheumatoid arthritis disease activity during monotherapy treatment with Actemra compared to adalimumab.
Behrens F, et al "Minimal disease activity is a stable measure of therapeutic response in psoriatic arthritis patients receiving treatment with adalimumab" 2018; doi:10.
Investigators repeated the analysis for VOYAGE II for 112 patients who switched from adalimumab to guselkumab.
The distribution volume (Vss) ranged from 4.7 to 6.0 L. The systemic clearance of adalimumab is approximately 12 mL/hr.
Who should not use this medication: People with allergy to adalimumab must not use it.